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The NFL regular season wraps up this weekend, as all 32 teams suit up one final time before the playoffs roll around. With no Thursday night or Monday night games on the docket, this week's 16 game slate takes place on Saturday (two games) and Sunday (14 games).

Last week, favorites and underdogs went a combined 8-8 ATS relative to Caesars Sportsbook's closing lines, yet another sign that the NFL betting market is uber-efficient and the point spread is always the great equalizer. Will we see a lopsided ATS mark for either favorites or 'dogs in Week 18?

With all 16 games taking place on Saturday or Sunday, bettors can look forward to an action-packed weekend of football. Each Week 18 matchup is a divisional game, and the teams' familiarity with each other is reflected in the betting market. Only one game (Cowboys-Commanders) has a double-digit spread, while the other 15 games have spreads of less than a touchdown. That means there's a good chance that this year's final "Witching Hour" on NFL RedZone will live up to the hype.

Below, we'll look at the latest odds for Week 18 from Caesars Sportsbook and offer up a couple of early bets to consider. Keep in mind these lines will move throughout the week as we get updates on the playing status of key starters and betting limits increase. Additionally, given the possibility of some teams resting key starters in Week 18, it's crucial to stay on top of about each team's approach.

NFL odds Week 18

Odds courtesy of Caesars Sportsbook

Game Spread
Pittsburgh Steelers at Baltimore Ravens BAL +4 (-110)
Houston Texans at Indianapolis Colts IND +1 (-110)
New York Jets at New England Patriots NE -1.5 (-110)
Cleveland Browns at Cincinnati Bengals CIN -7 (-110)
Tampa Bay Buccaneers at Carolina Panthers CAR +4.5 (-110)
Jacksonville Jaguars at Tennessee Titans TEN +5.5 (-110)
Atlanta Falcons at New Orleans Saints NO -3 (-120)
Minnesota Vikings at Detroit Lions DET -3.5 (-105)
Dallas Cowboys at Washington Commanders WAS +13 (-110)
Denver Broncos at Las Vegas Raiders LV -2.5 (-125)
Kansas City Chiefs at Los Angeles Chargers LAC -3.5 (-110)
Los Angeles Rams at San Francisco 49ers SF -4 (-110)
Seattle Seahawks at Arizona Cardinals ARI +3 (-120)
Chicago Bears at Green Bay Packers GB -3 (-105)
Philadelphia Eagles at New York Giants NYG +5 (-110)
Buffalo Bills at Miami Dolphins MIA +3 (-110)

NFL moneylines Week 18

Game Moneyline
Pittsburgh Steelers at Baltimore Ravens PIT -195 | BAL +162
Houston Texans at Indianapolis Colts HOU -130 | IND +110
New York Jets at New England Patriots NYJ +105 | NE -125
Cleveland Browns at Cincinnati Bengals CLE +250 | CIN -320
Tampa Bay Buccaneers at Carolina Panthers TB -225 | CAR +92
Jacksonville Jaguars at Tennessee Titans JAX -235 | TEN +192
Atlanta Falcons at New Orleans Saints ATL +143 | NO -170
Minnesota Vikings at Detroit Lions MIN +162 | DET -195
Dallas Cowboys at Washington Commanders DAL -800 | WAS +550
Denver Broncos at Las Vegas Raiders DEN +135 | LV -160
Kansas City Chiefs at Los Angeles Chargers KC +15 | LAC -190
Los Angeles Rams at San Francisco 49ers LAR +170 | SF -205
Seattle Seahawks at Arizona Cardinals SEA -135 | ARI +115
Chicago Bears at Green Bay Packers CHI +135 | GB -160
Philadelphia Eagles at New York Giants PHI -240 | NYG +196
Buffalo Bills at Miami Dolphins BUF -165 | MIA +140

NFL over/unders Week 18

Game Over/Under
Pittsburgh Steelers at Baltimore Ravens 35.5
Houston Texans at Indianapolis Colts 47.5
New York Jets at New England Patriots 30.5
Cleveland Browns at Cincinnati Bengals 37.5
Tampa Bay Buccaneers at Carolina Panthers 37.5
Jacksonville Jaguars at Tennessee Titans 40
Atlanta Falcons at New Orleans Saints 42
Minnesota Vikings at Detroit Lions 45.5
Dallas Cowboys at Washington Commanders 46
Denver Broncos at Las Vegas Raiders 38
Kansas City Chiefs at Los Angeles Chargers 35
Los Angeles Rams at San Francisco 49ers 41
Seattle Seahawks at Arizona Cardinals 47.5
Chicago Bears at Green Bay Packers 44
Philadelphia Eagles at New York Giants 42
Buffalo Bills at Miami Dolphins 49.5

NFL best bets for Week 18

*Odds and analysis as of Tuesday 1/2*

Saints -3.5 (-110) vs. Falcons

While it's been hard to get a read on the Saints this season, we're hoping their inspired Week 17 road win over the Buccaneers trickles over into Sunday's season finale against the Falcons. Considering Atlanta's dealing with some uncertainty at QB after Taylor Heinicke exited in the second half of last week's loss in Chicago with an ankle injury, it's hard to envision a strong offensive output from Arthur Smith's offense here. We'll lay the relatively short spread to back the Saints to keep their playoff hopes alive.

Bills -3 (-110) at Dolphins

The Bills' late-season resurgence puts them in the driver's seat to not only win the AFC East, but also to earn the conference's No. 2 seed if they take care of business in South Beach on Sunday night. There's always a chance that Josh Allen's turnover issues rear their ugly head and effectively end the Bills' season, but we're hoping Allen plays clean football like he did in Buffalo's 48-20 drubbing over Miami back in Week 4.

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Author(s)
Nick Musial Photo

Nick Musial is a Content Producer at The Sporting News. He recently joined the team after studying sport management and journalism at the University of Kansas. Nick’s an avid sports bettor who’s always looking for value.